Why do two women, with nearly identical hormone levels, lab results and lifestyles have completely different experiences during perimenopause?
One might feel anxious, foggy, and wired-but-tired. The other, is relatively fine. The symptom diversity and severity of perimenopause as puzzled both women and clinicians alike. Often the cause is hinted at lifestyle choices, but emerging science offers another powerful insight that to date, hasn’t been considered: how you go through perimenopause is also determined by genetics.
Perimenopause Hormonal shifts are not just “female signals.” These hormones are messengers that influence everything from your mood and metabolism to sleep, brain function, inflammation, skin, and cognition.
We now know that single nucleotide polymorphisms (SNPs)—tiny variations in your DNA – can dramatically shape how your body creates, uses, and clears hormones like estrogen, progesterone, testosterone, and cortisol.
That means:
• Two women can have identical hormone levels.
• But different sensitivities, detox pathways, neurotransmitter activity, and receptor functions.
•Resulting in completely different symptoms, risks, and responses to treatment.
At Willbe, we call this field Hormogenetics™ and Hormogenomics™ the study of how your inherited gene variants influence your hormonal reactivity, detoxification, receptor sensitivity, and symptom profile.
It helps us answer questions like:
• Why does one woman thrive on bioidentical hormone therapy while another crashes?
• Why is a clean lifestyle effective for some but not others?
• Why are some women naturally more resilient to hormonal decline?
This is exactly why we developed FemGene™: the first genetic test designed specifically for female hormone health during perimenopause.
FemGene™ maps 350+ SNPs across 125 genes into functional clusters, helping us understand:
• Why your symptoms are showing up now
• How your body metabolises and responds to hormones
• What types of treatment or lifestyle changes will actually work for you
It also reveals your Hormone Archetype™ – whether you’re the Resilient, the Sensitive, or the Silent Woman in your hormone response rooted in genetics.
© 2025 — Willbe, All rights reserved. Willbe & FemGene® are Trade Marks registered to Willbe Group Ltd. This product is not intended to diagnose, treat, cure, or prevent any disease.
